MovDisordV3, Main, Exploration, bibRecord, 001216

Alcohol and Risk of Parkinson's Disease in a Large, Prospective Cohort of Men and Women

Identifieur interne : 001216 ( Main/Exploration ); précédent : 001215; suivant : 001217

Alcohol and Risk of Parkinson's Disease in a Large, Prospective Cohort of Men and Women

Auteurs : Natalia Palacios [États-Unis] ; XIANG GAO [États-Unis] ; Eilis O'Reilly [États-Unis] ; Michael Schwarzschild [États-Unis] ; Marjorie L. Mccullough [États-Unis] ; Tinisha Mayo [États-Unis] ; Susan M. Gapstur [États-Unis] ; Alberto A. Ascherio [États-Unis]

Source :

Movement disorders [ 0885-3185 ] ; 2012.

RBID : Pascal:12-0315931

Descripteurs français

Pascal (Inist)
- Maladie de Parkinson, Pathologie du système nerveux, Alcool, Facteur risque, Prospective, Homme, Epidémiologie.
Wicri :
- geographic : États-Unis.
- topic : Alcool, Prospective, Homme.

English descriptors

KwdEn :
- Aged, Alcohol, Alcohol Drinking (epidemiology), Alcoholic Beverages, Beer, Coffee, Cohort Studies, Diet, Educational Status, Epidemiology, Female, Follow-Up Studies, Human, Humans, Male, Middle Aged, Nervous system diseases, Nutritional Status, Parkinson Disease (epidemiology), Parkinson disease, Proportional Hazards Models, Prospective, Prospective Studies, Questionnaires, Risk, Risk factor, Sex Factors, Smoking (epidemiology), Socioeconomic Factors, United States (epidemiology), Wine.
MESH :
- chemical : Coffee.
- geographic , epidemiology : United States.
- epidemiology : Alcohol Drinking, Parkinson Disease, Smoking.
- Aged, Alcoholic Beverages, Beer, Cohort Studies, Diet, Educational Status, Female, Follow-Up Studies, Humans, Male, Middle Aged, Nutritional Status, Proportional Hazards Models, Prospective Studies, Questionnaires, Risk, Sex Factors, Socioeconomic Factors, Wine.

Abstract

Addictive behaviors, such as cigarette smoking and coffee drinking, have been associated with a reduced risk of Parkinson's disease (PD). Whether alcohol consumption is also associated with PD risk is less certain. We prospectively followed 132,403 participants in the Cancer Prevention Study II Nutrition Cohort from 1992 to 2005. Alcohol intake was assessed at baseline. Incident cases of PD (n = 605; 389 male and 216 female) were confirmed by treating physicians and medical record review. Relative risks (RRs) were estimated using proportional hazards models, adjusting for age, smoking, and other risk factors. Alcohol consumption was not significantly associated with PD risk. After adjustment for age, smoking, and other risk factors, the RR comparing men consuming 30 or more grams of alcohol per day (highest category) to nondrinker men was 1.29 (95% confidence interval [Cl]: 0.90, 1.86; P trend: 0.40), and the RR comparing women consuming 15 or more grams of alcohol (highest category) per day to nondrinker women was 0.77 (95% Cl: 0.41, 1.45; P trend: 0.87). Consumption of beer, wine, or liquor was also not associated with PD risk. The results of this large, prospective study do not support an association between alcohol intake and risk of PD.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548327

Affiliations:

Le document en format XML

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<series><title level="j" type="main">Movement disorders</title>
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<term>Alcoholic Beverages</term>
<term>Beer</term>
<term>Coffee</term>
<term>Cohort Studies</term>
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<term>Humans</term>
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<term>Parkinson Disease (epidemiology)</term>
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<term>Prospective</term>
<term>Prospective Studies</term>
<term>Questionnaires</term>
<term>Risk</term>
<term>Risk factor</term>
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<term>Smoking (epidemiology)</term>
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<term>Follow-Up Studies</term>
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<keywords scheme="Pascal" xml:lang="fr"><term>Maladie de Parkinson</term>
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<front><div type="abstract" xml:lang="en">Addictive behaviors, such as cigarette smoking and coffee drinking, have been associated with a reduced risk of Parkinson's disease (PD). Whether alcohol consumption is also associated with PD risk is less certain. We prospectively followed 132,403 participants in the Cancer Prevention Study II Nutrition Cohort from 1992 to 2005. Alcohol intake was assessed at baseline. Incident cases of PD (n = 605; 389 male and 216 female) were confirmed by treating physicians and medical record review. Relative risks (RRs) were estimated using proportional hazards models, adjusting for age, smoking, and other risk factors. Alcohol consumption was not significantly associated with PD risk. After adjustment for age, smoking, and other risk factors, the RR comparing men consuming 30 or more grams of alcohol per day (highest category) to nondrinker men was 1.29 (95% confidence interval [Cl]: 0.90, 1.86; P trend: 0.40), and the RR comparing women consuming 15 or more grams of alcohol (highest category) per day to nondrinker women was 0.77 (95% Cl: 0.41, 1.45; P trend: 0.87). Consumption of beer, wine, or liquor was also not associated with PD risk. The results of this large, prospective study do not support an association between alcohol intake and risk of PD.</div>
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<tree><country name="États-Unis"><region name="Massachusetts"><name sortKey="Palacios, Natalia" sort="Palacios, Natalia" uniqKey="Palacios N" first="Natalia" last="Palacios">Natalia Palacios</name>
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<name sortKey="Ascherio, Alberto A" sort="Ascherio, Alberto A" uniqKey="Ascherio A" first="Alberto A." last="Ascherio">Alberto A. Ascherio</name>
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<name sortKey="Xiang Gao" sort="Xiang Gao" uniqKey="Xiang Gao" last="Xiang Gao">XIANG GAO</name>
<name sortKey="Xiang Gao" sort="Xiang Gao" uniqKey="Xiang Gao" last="Xiang Gao">XIANG GAO</name>
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   |wiki=    Wicri/Santé
   |area=    MovDisordV3
   |flux=    Main
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   |clé=     Pascal:12-0315931
   |texte=   Alcohol and Risk of Parkinson's Disease in a Large, Prospective Cohort of Men and Women
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Movement Disorders (revue)

Alcohol and Risk of Parkinson's Disease in a Large, Prospective Cohort of Men and Women

Alcohol and Risk of Parkinson's Disease in a Large, Prospective Cohort of Men and Women

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	Movement Disorders (revue)
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